https://doi.org/10.4081/ijwc.2019.46

The L-PRF membrane and its derivatives useful in wound care surgery

Vol. 3 No. 1 (2019)
Submitted: December 4, 2018
Accepted: January 21, 2019
Published: February 4, 2019
Growth factors, Fibrin-rich in leukocytes and platelets, Fibrin-rich in injectable platelets, Stem cells
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Authors

Alessandro Crisci
alessandrocrisci@libero.it
Unit of Dermosurgery Cutaneous Transplantations and Hard-to-Heal Wound, "Villa Fiorita" Private Hospital, Aversa (CE); School of Medicine, University of Salerno, Fisciano (SA); Institute for the Studies and Care of Diabetics, Abetaia, Casagiove, Italy.
Carmela Rescigno
School of Medicine, University of Salerno, Fisciano (SA), Italy.
Michela Crisci
Faculty of Medicine and Surgery, Vasile Goldis Western University of Arad, Arad, Romania.

Growing multidisciplinary field of tissue engineering aims to regenerate, improve or replace predictably damaged or missing tissues for a variety of conditions caused by trauma, disease and old age. To ensure that tissue engineering methods are widely applicable in the clinical setting, it is necessary to modify them in such a way that they are readily available and relatively easy to use in daily clinical routine. Therefore, the steps between preparation and application must be minimized and optimized to make them realistic implementation. General objective of developing platelet concentrates of natural origin can be produced close to the patient and accelerate the implantation process, being financially realistic for the patient and the health system. Fibrin rich in platelets and leukocytes (PRF) and its derivatives have been used in a wide variety of medical fields for soft tissue regeneration. In conclusion, the results of this systematic review highlight the positive effects of PRF on wound healing after regenerative therapy for the management of various soft tissue defects found in wound care.

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How to Cite

Crisci, A., Rescigno, C., & Crisci, M. (2019). The L-PRF membrane and its derivatives useful in wound care surgery. Italian Journal of Wound Care, 3(1). https://doi.org/10.4081/ijwc.2019.46

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