https://doi.org/10.4081/ijwc.2022.92
Clinical evaluation of the efficacy and tolerability of a new device based on of Rigenase® and polyhexanide in the treatment of chronic skin lesions
Submitted: September 29, 2022
Accepted: November 21, 2022
Published: December 22, 2022
Accepted: November 21, 2022
Abstract Views: 509
PDF (Italiano): 218
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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studio caso controllo di una medicazione composta da Rigenase© (stimolina di origina vegetale) addizionata di poliesanide, su un nuovo supporto in PET in triplo strato nel trattamento di lesioni cutanee croniche dell’arto inferiore. Scopo dello studio la valutazione in termini di riparazione e controllo del bioburden Batterico. Sono stati arruolati 20 pazienti con un periodo di run in di 6 settimane con terapia secondo i gold standard; a seguire un analogo periodo di trattamento con la medicazione in studio. I punti in esame sono stati l’evoluzione dell’area, misurata con un sistema basato su intelligenza artificiale come primario. End poin seocondari: livello di infezione/colonizzazione, WBP e dolore, tutti raccolti mediante scale validate. I dati raccolti inerentemente all’area hanno dimostrato una differenza statisticamente significativa (p<0.0001). differenze significative si sono evidenziate anche in termini di segni di infezione (p<0.001), WBP score (p<0.001) e dolore con NRS (p<0.0001). Non si sono riscontrati eventi avversi od effetti collaterali. Gli autori concludono che la medicazione dimostra una elevata capacità di stimolare la ripresa dei fenomeni riparativi in lesioni con scarsa tendenza spontanea alla riparazione.
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How to Cite
Ricci, E., & Pittarello, M. (2022). Clinical evaluation of the efficacy and tolerability of a new device based on of Rigenase® and polyhexanide in the treatment of chronic skin lesions. Italian Journal of Wound Care, 6(2). https://doi.org/10.4081/ijwc.2022.92
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