https://doi.org/10.4081/ijwc.2023.96
Topical application of cannabinoid-based galenic preparations for pain treatment in chronic leg ulcer: case reports
Submitted: February 11, 2023
Accepted: March 7, 2023
Published: April 6, 2023
Accepted: March 7, 2023
Abstract Views: 407
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Chronic leg ulcers are disabling and often painful. Venous leg ulcers (VLU) affect mainly the elderly and represent a condition of discomfort and poor quality of life. Pain at dressing changes, for these patients, is a particularly feared and stressful procedure leading to anxiety. Topical cannabinoid treatment is an innovative treatment choice for pain modulation and reduction when treating VLU. A Canadian study showed promising results when using topical application of cannabis in patients with pyoderma gangrenous. We therefore proposed to conduct a study on cannabinoids in the management of VLU with two types of galenic preparations. Three patients were treated, with Cannabis Oil Flos (Bedrocan®) (19-22% THC; CBD<1%). The Cannabis Oil Flos showed good effectiveness in reducing painful symptoms and reducing the need for oral analgesics.
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Hellström A, Nilsson C, Nilsson A, Fagerström C. Leg ulcers in older people: a national study addressing variation in diagnosis, pain and sleep disturbance. BMC Geriatrics 2016;16:25.
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Pannier F, Rabe E. Differential diagnosis of leg ulcers. Phlebology 2013;28:55-60.
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How to Cite
Polignano, R., Gatto, R., Ruffino, I., Pavanelli, A., & Falciani, F. (2023). Topical application of cannabinoid-based galenic preparations for pain treatment in chronic leg ulcer: case reports. Italian Journal of Wound Care, 7(1). https://doi.org/10.4081/ijwc.2023.96
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