https://doi.org/10.4081/ijwc.2023.96
Topical application of cannabinoid-based galenic preparations for pain treatment in chronic leg ulcer: case reports
Accepted: March 7, 2023
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Authors
Chronic leg ulcers are disabling and often painful. Venous leg ulcers (VLU) affect mainly the elderly and represent a condition of discomfort and poor quality of life. Pain at dressing changes, for these patients, is a particularly feared and stressful procedure leading to anxiety. Topical cannabinoid treatment is an innovative treatment choice for pain modulation and reduction when treating VLU. A Canadian study showed promising results when using topical application of cannabis in patients with pyoderma gangrenous. We therefore proposed to conduct a study on cannabinoids in the management of VLU with two types of galenic preparations. Three patients were treated, with Cannabis Oil Flos (Bedrocan®) (19-22% THC; CBD<1%). The Cannabis Oil Flos showed good effectiveness in reducing painful symptoms and reducing the need for oral analgesics.
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