https://doi.org/10.4081/ijwc.2023.96

Topical application of cannabinoid-based galenic preparations for pain treatment in chronic leg ulcer: case reports

Vol. 7 No. 1 (2023)
Submitted: February 11, 2023
Accepted: March 7, 2023
Published: April 6, 2023
CBD, THC, topical medical cannabis, wound care, leg ulcers
Abstract Views: 407
PDF (Italiano): 210
PDF: 58
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Authors

Roberto Polignano
roberto.polignano@uslcentro.toscana.it
https://orcid.org/0000-0003-2389-6033
SOS Vascular Medicine, Nuovo S. Giovanni di Dio Hospital, Italy.
Roberta Gatto
Galenic Laboratory, Pharmacy of the S. Maria Nuova Hospital, Italy.
Irene Ruffino
Galenic Laboratory, Pharmacy of the S. Maria Nuova Hospital, Italy.
Alessandra Pavanelli
Wound Care Team, Nuovo S.Giovanni di Dio Hospital, Firenze, Italy.
Francesca Falciani
Wound Care Team, Nuovo S.Giovanni di Dio Hospital, Firenze, Italy.

Chronic leg ulcers are disabling and often painful. Venous leg ulcers (VLU) affect mainly the elderly and represent a condition of discomfort and poor quality of life. Pain at dressing changes, for these patients, is a particularly feared and stressful procedure leading to anxiety. Topical cannabinoid treatment is an innovative treatment choice for pain modulation and reduction when treating VLU. A Canadian study showed promising results when using topical application of cannabis in patients with pyoderma gangrenous. We therefore proposed to conduct a study on cannabinoids in the management of VLU with two types of galenic preparations. Three patients were treated, with Cannabis Oil Flos (Bedrocan®) (19-22% THC; CBD<1%). The Cannabis Oil Flos showed good effectiveness in reducing painful symptoms and reducing the need for oral analgesics.

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How to Cite

Polignano, R., Gatto, R., Ruffino, I., Pavanelli, A., & Falciani, F. (2023). Topical application of cannabinoid-based galenic preparations for pain treatment in chronic leg ulcer: case reports. Italian Journal of Wound Care, 7(1). https://doi.org/10.4081/ijwc.2023.96
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