https://doi.org/10.4081/ijwc.2024.111

Use of the Lumiheal device in the treatment of contaminated wounds

Vol. 8 No. 1 (2024)
Submitted: February 14, 2024
Accepted: May 20, 2024
Published: May 31, 2024
Biophotonics, fluorescence biomodulation, photobiomodulation, phototherapy
Abstract Views: 190
PDF: 120
Supplementary Materials (Italiano): 24
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Authors

Elia Ricci
eliaricci@tin.it
Unità di Vulnology Unit, Policlinico di Monza, Clinica S. Rita di Vercelli, Clinica Eporediese di Ivrea, Policlinico di Monza, Clinica S. Rita di Vercelli, Clinica Eporediese di Ivrea, Italy.
Monica Pittarello
Vulnology Unit, Policlinico di Monza, Clinica S. Rita di Vercelli, Clinica Eporediese di Ivrea, Italy.

Observational study on patients with chronic wounds of lower limb colonized or critically colonized treated with biophotonic therapy. Ten patients with venous or inflammatory ulcers were enrolled. All enrolled patients were treated once a week with a double application of the therapy. The treatment period was 6 weeks, and a final assessment was performed at 12 weeks. The data collected were: evaluation of the bacterial load using the Moleculight system; and bacterial load with semi-quantitative method via swab according to Levine. Four types of bacteria were studied, Staphylococci, Pseudomonas, Enterococci, and Proteus. Ph measurement and evaluation of the Cutting and Harding score for infections. Results show a good performance in the control of bioburden and a reduction of clinical signs in 2 weeks. The secondary point was a reduction of pain and an improvement of perilesional tissue. The reduction of the area was batter in venous etiology wounds by close to 40% and a healing rate of 33%, good result but lower in inflammatory wounds. The authors hypothesize a marked activity on factors linked to local inflammation.

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Crossref
Scopus
Google Scholar
Europe PMC
Nikolis A, Grimard D, Pesant Y, et al. A prospective case series evaluating the safety and efficacy of the Klox BioPhotonic System in venous leg ulcers. Chronic Wound Care Manag Res 2016:3:101-111. DOI: https://doi.org/10.2147/CWCMR.S104391
Romanelli M, Piaggesi A, Scapagnini G, et al. Evaluation of fluorescence biomodulation in the real-life management of chronic wounds: the EUREKA trial. J Wound Care 2018;27:744-53. DOI: https://doi.org/10.12968/jowc.2018.27.11.744
Sutherland JC. Biological effects of polychromatic light. Photochem Photobiol 2002;76:164–70. DOI: https://doi.org/10.1562/0031-8655(2002)076<0164:BEOPL>2.0.CO;2
Kim HP. Lightening up light therapy: Activation of retrograde signaling pathway by photobiomodulation. Biomol Ther (Seoul) 2014;22:491–6. DOI: https://doi.org/10.4062/biomolther.2014.083
Huang YY, Sharma SK, Carroll J, Hamblin MR. Biphasic dose response in low level light therapy - an update. Dose Response 2011;9:602–18. DOI: https://doi.org/10.2203/dose-response.11-009.Hamblin
Fathabadie FF, Bayat M, Amini A, et al. Effects of pulsed infra-red low level-laser irradiation on mast cells number and degranulation in open skin wound healing of healthy and streptozotocin-induced diabetic rats. J Cosmet Laser Ther 2013;15:294–304. DOI: https://doi.org/10.3109/14764172.2013.764435
AlGhamdi KM, Kumar A, Moussa NA. Low-level laser therapy: a useful technique for enhancing the proliferation of various cultured cells. Lasers Med Sci 2012;27:237–49. DOI: https://doi.org/10.1007/s10103-011-0885-2
Enwemeka CS, Parker JC, Dowdy DS, et al. The efficacy of low-power lasers in tissue repair and pain control: a meta-analysis study. Photomed Laser Surg 2004;22:323–9. DOI: https://doi.org/10.1089/1549541041797841
Mittermayr R, Osipov A, Piskernik C, et al. Blue laser light increases perfusion of a skin flap via release of nitric oxide from hemoglobin. Mol Med 2007;13:22–9. DOI: https://doi.org/10.2119/2006-00035.Mittermayr
Jenkins ML, O'Neal E. Pressure ulcer prevalence and incidence in acute care. Adv Skin Wound Care 2010;23:556-9. DOI: https://doi.org/10.1097/01.ASW.0000391184.43845.c1
Margolis DJ, Bilker W, Santanna J, Baumgarten M. Venous leg ulcer: incidence and prevalence in the elderly. J Am Acad Dermatol 2002;46:381–6. DOI: https://doi.org/10.1067/mjd.2002.121739
Kirsner RS, Vivas AC. Lower-extremity ulcers: diagnosis and manage¬ment. Br J Dermatol 2015;173:379–90. DOI: https://doi.org/10.1111/bjd.13953
Jones KR, Fennie K, Lenihan A. Evidence-based management of chronic wounds. Adv Skin Wound Care 2007;20:591–600. DOI: https://doi.org/10.1097/01.ASW.0000284936.32707.8d
Oliverio J, Gero E, Whitacre KL, Rankin J. Wound care algorithm: diagnosis and treatment. Adv Skin Wound Care 2016;29:65–72. DOI: https://doi.org/10.1097/01.ASW.0000473132.88076.af
Principles of best practice: Wound infection in clinical practice. An international consensus. London: MEP Ltd, 2008. Available from www.mepltd.co.uk
Natarajan S, Williamson D, Stiltz AJ, Harding K. Advances in wound care and healing technology. Am J Clin Dermatol 2000;1:269–75. DOI: https://doi.org/10.2165/00128071-200001050-00002
De Freitas LF, Hamblin MR. Proposed mechanisms of photobiomodu¬lation or low-level light therapy. IEEE J Sel Top Quantum Electron 2016;22:7000417. DOI: https://doi.org/10.1109/JSTQE.2016.2561201
Enwemeka CS, Parker JC, Dowdy DS, et al. The efficacy of low-power lasers in tissue repair and pain control: a meta-analysis study. Photomed Laser Surg 2004;22:323–9. DOI: https://doi.org/10.1089/1549541041797841
Armstrong DG, Edmonds ME, Serena TE. Point-of-care fluorescence imaging reveals extent of bacterial load in diabetic foot ulcers. Int Wound J 2023;20:554-66. DOI: https://doi.org/10.1111/iwj.14080
Rondas AALM, Schols JMGA, Halfens RJG, Stobberingh EE. Swab versus biopsy for the diagnosis of chronic infected wounds. Adv Skin Wound Care 2013;26:211-9. DOI: https://doi.org/10.1097/01.ASW.0000428984.58483.aa
Miller C, Karimi L, Donohue L, Kapp S. Interrater and intrarater reliability of silhouette wound imaging device. Adv Skin Wound Care 2012;25:513-8. DOI: https://doi.org/10.1097/01.ASW.0000422626.25031.b8
Cutting KF, Harding KG. Criteria for identifying wound infection. J Wound Care 1994;3:198-201. DOI: https://doi.org/10.12968/jowc.1994.3.4.198
Falanga V. Classification for wound bed preparation and stimulation of chronic wounds. Wound Repair Regen 2000;8:347-52. DOI: https://doi.org/10.1111/j.1524-475X.2000.00347.x
Breivick H, Borchgrevink PC, Allen SM, et al. Assesment of pain. B J Anaesth 2008;101:17-24. DOI: https://doi.org/10.1093/bja/aen103
Harries RL, Bosanquet DC, Harding KG. Wound bed preparation: TIME for an update. Int Wound J 2016;13:8–14. DOI: https://doi.org/10.1111/iwj.12662

How to Cite

Ricci, E., & Pittarello, M. (2024). Use of the Lumiheal device in the treatment of contaminated wounds. Italian Journal of Wound Care, 8(1). https://doi.org/10.4081/ijwc.2024.111
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