https://doi.org/10.4081/ijwc.2023.103
Analisi citomorfologica di fibrina ricca di piastrine liquida prodotta con centrifuga ad angolo fisso DUO (Process, Francia) per l’uso nella terapia rigenerativa delle ulcere cutanee
Ricevuto: 3 giugno 2023
Accettato: 16 ottobre 2023
Published: 14 dicembre 2023
Accettato: 16 ottobre 2023
Abstract Views: 159
PDF (English): 43
Supplementary Materials (English): 14
PDF: 68
Materiali Supplementari: 18
Supplementary Materials (English): 14
PDF: 68
Materiali Supplementari: 18
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Autori
La fibrina ricca di piastrine (PRF) liquida è un concentrato piastrinico di seconda generazione iniettabile ricco di piastrine, leucociti e fibrinogeno ottenuto per centrifugazione del sangue autologo. Lo scopo di questo studio è analizzare il contenuto cellulare e di fibrinogeno di vari tipi di PRF Liquido (C-PRF liquid, A-PRF liquid, i-PRF, fibrinogeno liquido) ottenuti con l’uso di centrifuga ad angolo fisso DUO (PRF DUO, Process per PRF, Nizza, Francia) con provette Fibrinogeno Liquido (FL) Vacumed (cod. 44909) e/o provetta originale S-PRF Sticky. È stato riscontrato un accumulo medio di Trombociti di quasi 1,5 volte rispetto al sangue intero. A causa dell’elevata concentrazione di Piastrine, i PRF-Liquid contengono importanti fattori di crescita per la rigenerazione tissutale. In questo studio preliminare abbiamo evidenziato che il tipo di PRF Liquido a maggiore contenuto di piastrine (126.3% vs. 109.5%), monociti (127.6% vs. 84.6%), con un sufficiente contenuto di linfociti (192.9% vs. 242.1%) e granulociti neutrofili (64.6% vs. 64.8%) e di fibrinogeno (67.9% vs. 87.3%), è il i-PRF (700 rpm×5 min) ottenuto con provetta Vacumed FL (cod. 44909) con differenze statisticamente non significative rispetto al sangue intero, mentre è maggiore il contenuto di Linfociti e Fibrinogeno presente in i-PRF (700 rpm×5’) ottenuto con provetta PRF-S-Sticky. Molto minore, nel confronto, risulta il contenuto di cellule e fibrinogeno ottenuto con i due metodi di preparazione del PRP. Ciò indica che il PRF liquido più adatto ad essere utilizzato in vari casi di rigenerazione dei tessuti come l’estetica del viso, l’iniezione intrarticolare, l’iniezione periulcerativa, etc. è il i-PRF (700 rpm×5 min) ottenuto con provetta Vacumed FL.
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Come citare
Crisci, M., Lepore, G., Feleppa, F., Crisci, A., & Flagiello, F. (2023). Analisi citomorfologica di fibrina ricca di piastrine liquida prodotta con centrifuga ad angolo fisso DUO (Process, Francia) per l’uso nella terapia rigenerativa delle ulcere cutanee. Italian Journal of Wound Care, 7(3). https://doi.org/10.4081/ijwc.2023.103
Copyright (c) 2023 Gli Autori
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